Abstract
SummaryDiabetes Mellitus may lead to alterations in the eyes, kidneys, cranial nerves, peripheral nerves, ears etc. The cognitive function also seems to be compromised in subjects presented with Diabetes Mellitus, since the cortical and subcortical structures responsible for this function are hindered in some insulin-dependent patients. The cognitive potential P300 has been used as an objective procedure to assess cerebral cognitive functions.AimTo analyze the sensitivity of P300 cognitive potential for the detection of alterations on the auditory cortex secondary to Diabetes Mellitus.Study designtransversal cohort.Material and MethodSixteen diabetic subjects of both genders aged 7 to 71 years, and seventeen non-diabetic individuals at the same age range participated in this study. The evaluation procedures were pure tone audiometry (PTA) and P300 cognitive potential. Glycemia of the group presented with Diabetes was assessed prior to applying P300.ResultsNo statistically significant difference was shown for PTA results. A statically significant difference was observed between groups when analyzing the latency of P300 component measured in Fz. There was a correlation between glycemia and latency and amplitude of P300.ConclusionThe investigation of the cognitive potential of P300 is an important procedure for prevention and early diagnosis of neurological changes in individuals presented with Diabetes Mellitus.
Highlights
Diabetes mellitus is a chronic condition whose onset is given when the pancreas does not produce enough amount of insulin or when the body does not manage to effectively use the produced insulin
Metabolic control is normally obtained with diet, physical exercises and/or concomitant use of oral hypoglycemic agents, and insulin may be used for treatment; 3) secondary diabetes - type of diabetes in which the causal factor is known, such as some genetic defects that result in abnormalities of beta cell function or insulin action, some pancreatic and endocrine diseases, or those caused by some drugs; 4) gestational diabetes - it is primarily diagnosed during pregnancy and it may disappear at the end of the pregnancy period
We show the results of the statistical analysis to compare control and diabetic groups using Variance Analysis in repetitive measurements, whose factors were tested and analyzed in groups, plus auditory thresholds obtained in pure tone audiometry (PTA) for each tested frequency
Summary
Diabetes mellitus is a chronic condition whose onset is given when the pancreas does not produce enough amount of insulin or when the body does not manage to effectively use the produced insulin. Metabolic control is normally obtained with diet, physical exercises and/or concomitant use of oral hypoglycemic agents, and insulin may be used for treatment; 3) secondary diabetes - type of diabetes in which the causal factor is known, such as some genetic defects that result in abnormalities of beta cell function or insulin action, some pancreatic and endocrine diseases, or those caused by some drugs; 4) gestational diabetes - it is primarily diagnosed during pregnancy and it may disappear at the end of the pregnancy period
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
