Abstract
Objective: to evaluate cognitive functions and drug correction of identified impairments in heroin users. Patients and methods. Thirty-two patients (7 women and 25 men) aged 18 to 45 years who had used heroin for 1—3 years were examined using the mini-mental state examination (MMSE), the techniques of «memorizing words» and «excluding words», the tests of «information-memory-concentration», quantitative assessment of clock drawing, and the frontal assessment battery. The detected cognitive impairments were corrected with the standardized Ginkgo Biloba extract (EGb 761 ®, Tanakan ®). Results. Cognitive impairments were found in all the patients: moderate cognitive disorders in 68.8% and mild dementia in 31.2%; thinking disorders were most noticeable; decreased attention, frontal lobe dysfunction, and visual spatial impairments were detectable. After a course of therapy with tanakan (120—240 g/day according to the degree of cognitive impairments for 3 months), there was a significant improvement in MMSE scores, thought, concentration, memory; however, they failed to achieve the scores in the control group consisting of 10 apparently healthy individuals of the same age and sex.
Highlights
Цель исследования – оценка когнитивных функций и лекарственная коррекция выявленных нарушений у лиц, употребляющих героин
The detected cognitive impairments were corrected with the standardized Ginkgo Biloba extract (EGb 761®, Tanakan®)
Cognitive impairments were found in all the patients: moderate cognitive disorders in 68.8% and mild dementia in 31.2%; thinking disorders were most noticeable; decreased attention, frontal lobe dysfunction, and visual spatial impairments were detectable
Summary
Mas J.L., Chatellier G., Beyssen B. et al Endarterectomy versus stenting in patients with symptomatic severe carotid stenosis. Brott T.G., Hobson R.W. 2nd, Howard G. et al Stenting versus endarterectomy for treatment of carotid-artery stenosis. Когнитивные расстройства у лиц молодого возраста с опиоидной зависимостью и их коррекция. Цель исследования – оценка когнитивных функций и лекарственная коррекция выявленных нарушений у лиц, употребляющих героин. Когнитивные расстройства выявлены у всех больных: у 68,8% – умеренные нарушения, у 31,2% – деменция легкой степени. После курса лечения танаканом (по 120–240 мг/сут, в зависимости от выраженности когнитивных нарушений, в течение 3 мес) установлено достоверное улучшение показателей КШОПС, мышления, концентрации внимания, памяти, однако они не достигли параметров контрольной группы, состоявшей из 10 практически здоровых соответствующего возраста и пола.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
