Abstract
To evaluate the neuropsychological profile and determine the risk of cognitive impairment in patients with arterial hypertension depending on the presence or absence of risk factors for chronic renal disease at the sanatorium stage. 200 patients with arterial hypertension of 1st-2nd degree, stage II, risk 2-3 were examined. The level of microalbuminuria, creatinine in blood serum was investigated, the rate of glomerular filtration was calculated. Cognitive functions were evaluated using neuropsychological tests of 10 words, 5 figures, counting down, tables Shulte, MMSE, FAB. Risk factors for chronic kidney disease were first discovered in 48% of patients. It was revealed that in patients with arterial hypertension and risk factors of chronic kidney disease the risk of occurrence and development of cognitive disorders is 1.46 times higher, the degree of reduction in indicators of arbitrary attention, speed of mental performance, auditory memory is more expressed than in patients with arterial hypertension alone. It was shown that in patients with arterial hypertension and risk factors of chronic kidney disease a moderate degree of multifunctional variant of cognitive disturbances with memory decrease and neurodynamic disturbances is observed.
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