Abstract
The meta-analysis reported by Vermeulen et al. 1 Vermeulen T Lauwers T Van Diermen L et al. Cognitive deficits in older adults with psychotic depression: a meta-analysis. Am J Geriatr Psychiatry. 2019; 27: 1334-1344 Abstract Full Text Full Text PDF Scopus (12) Google Scholar demonstrates that geriatric patients with psychotic major depression (PD) perform more poorly than comparably aged older persons with nonpsychotic major depression (NPD). Between-group differences were identified in global cognition and most of the specific functions assessed. The report documents that the well-established cognitive impairment associated with geriatric NPD 2 Nebes RD Butters MA Mulsant BH et al. Decreased working memory and processing speed mediate cognitive impairment in geriatric depression. Psychol Med. 2000; 30: 679-691 Crossref PubMed Scopus (236) Google Scholar , 3 Butters MA Whyte EM Nebes RD et al. The nature and determinants of neuropsychological functioning in late-life depression. Arch Gen Psychiatry. 2004; 61: 587-595 Crossref PubMed Scopus (489) Google Scholar is more severe in PD. Their findings raise important questions: (1)Does the greater impairment in PD than NPD result from greater depression severity?
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
