Abstract
Cognitive enhancement in non-Alzheimer’s dementias has not been studied as extensively as that in Alzheimer’s dementia. This chapter reviews the research on cognitive enhancement for three types of dementia: vascular dementia, dementia with Lewy bodies, and frontal lobe dementia. The chapter reviews both pharmacological and nonpharmacological approaches for treatment of dementia. The focus is on randomized controlled trials for currently available medications, specifically cholinesterase inhibitors and memantine. Major advances in physical and cognitive rehabilitation during the past decade have inspired clinicians and researchers to explore the role of potential cognitive enhancers in different types of dementias. This chapter also examines the effects of therapeutic interventions such as exercise, physical rehabilitation, cognitive rehabilitation, and electrical stimulation of the brain on cognition in non-Alzheimer’s dementias.
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