Cognitive Dysfunction in Early and Late Onset Schizophrenia: A Comparative Study

Dr Rajendra Kumar Sharma Dr Rajendra Kumar Sharma,Supriya Sharma Supriya Sharma

doi:10.25215/0304.101

Abstract

The aim of this present study was to assess the cognitive dysfunctions among early onset schizophrenia and Late onset schizophrenia. Methods: The study was conducted at Ranchi Institute of Neuro- Psychiatry and Allied Sciences (RINPAS), Kanke, Ranchi. Based on purposive sampling method a group of forty male schizophrenic patients between the age range of 18 to 42 years were taken twenty patients were early onset schizophrenia (18 to 30 years) and twenty patients were of late onset of schizophrenia (31 to 42) years who were diagnosed according to the DCR, ICD – 10 were selected from different words of RINPAS. Similarly twenty normal controls were selected from different localities of Ranchi. Results: Significant result found on different domains. A normal control on VAIS was better than schizophrenic groups, between the schizophrenics groups the late onset schizophrenics performance better than early onset schizophrenics patient. The performance of normal controls on WAPIS-PR was better than schizophrenic groups, between the schizophrenics groups the late onset schizophrenics performance better than early onset schizophrenics patient. The performance of normal on controls on WCST was better than schizophrenic groups, between the schizophrenics groups the late onset schizophrenics performance better than early onset schizophrenics patient. Late onset schizophrenic patients performed better than early onset schizophrenic patients, indicating that late onset schizophrenics are relatively less impaired than early onset schizophrenics, with respect of cognitive function, as measured by IQ and WCST performance.

Highlights

The aim of this present study was to assess the cognitive dysfunctions among early onset schizophrenia and Late onset schizophrenia
Onset schizophrenia: Three-fourth of all schizophrenias begin with a prepsychoticprodromal phase, which lasts several times longer than the psychotic prophase
Twenty patients were of early onset schizophrenia (18 to 30 years) and twenty patients were of late onset of schizophrenia (31 to 42 years) Patients were diagnosed according to the DCR, ICD – 10 and have been selected from different words of RINPAS

Summary

Introduction

The aim of this present study was to assess the cognitive dysfunctions among early onset schizophrenia and Late onset schizophrenia. The performance of normal controls on WAPIS-PR was better than schizophrenic groups, between the schizophrenics groups the late onset schizophrenics performance better than early onset schizophrenics patient. The performance of normal on controls on WCST was better than schizophrenic groups, between the schizophrenics groups the late onset schizophrenics performance better than early onset schizophrenics patient. At this stage failure to reach the expected social status plays a greater role than steps of social decline, which gain in relevance after the main social roles have been acquired Due to their lower age of onset and probably their more frequent socially negative illness behaviour males are socially more disadvantaged in the early course of schizophrenia compared with females. Symptomatology and, surprisingly, type of onset does not seem to have any significant influence on the crudely measured two year outcome of social disability

Objectives

Methods

Conclusion