Abstract
Iridocorneal Endothelial Syndrome (ICE) is a unique ophthalmic disorder characterized by the presence of an abnormal corneal endothelium which leads to varying degrees of corneal edema, progressive iris atrophy and secondary angle closure glaucoma without pupillary block. Cogan Reese syndrome is one of the three clinical variants of Iridocorneal Endothelial Syndrome (ICE) characterized by nodular, pigmented lesions of the iris which are hallmark, and may be seen with the entire spectrum of corneal and other iris defects. Secondary glaucoma is the main sight threatening complication. Management depends on severity of ocular findings and is targeted to control secondary glaucoma medically and surgically. We hereby report two middle aged male patients who were diagnosed to have the Cogan-Reese variant of ICE Syndrome based on clinical findings.
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