Coffin Siris Syndrome with Significant Autistic Features.

doi:10.46940/scmcrj.01.1002

Abstract

Abstract Coffin Siris Syndrome is a rare genetic dysmorphic disorder that was first described by Coffin and Siris in 1970. It is associated with mental retardation and distinctive coarse facial features including wide nose, wide mouth with thick everted upper and lower lips, thick eyebrows and lashes, hirsutism/hypertrichosis. Sparse scalp hair particularly in the temporal areas. Coffin Siris syndrome has been reported only once in Iraq. The first Iraq patient with Coffin Siris syndrome (Al Mosawi AJ,2006) was also the first patient in the Arab. The occurrence of significant autistic features in form of pervasive developmental disorder or autism has been very infrequently reported in association with Coffin Siris syndrome. This aim to report which is most probably the seventh case of Coffin Siris Syndrome associated with significant autistic features. The case is the second case of this syndrome in Iraq which is also the case number 170 in the world.

Highlights

Coffin Siris Syndrome is a rare genetic dysmorphic hypertrichosis. 3-Sparse scalp hair in the disorder that was first described by Coffin and Siris in temporal areas 4-Feeding difficulties, slow growth, 1970. It is associated with mental retardation and hypotonia
Coffin Siris Syndrome is a rare genetic dysmorphic disorder that was first described by Coffin and Siris in 1970
Of pervasive developmental disorder or autism has been very infrequently reported in association with

Summary

Coffin Siris Syndrome with Significant Autistic Features

Coffin Siris Syndrome is a rare genetic dysmorphic hypertrichosis. 3-Sparse scalp hair in the disorder that was first described by Coffin and Siris in temporal areas 4-Feeding difficulties, slow growth, 1970. 3-Sparse scalp hair in the disorder that was first described by Coffin and Siris in temporal areas 4-Feeding difficulties, slow growth, 1970. It is associated with mental retardation and hypotonia. The occurrence of significant autistic features in form in form of pervasive developmental disorder or autism of pervasive developmental disorder or autism has has been very infrequently reported in association been very infrequently reported in association with with Coffin Siris syndrome.

Introduction

Discussion

Childhood Autism in a female with Coffin Siris