Abstract
A suitable amount of CoFe2O4 nanoparticle (CoFe2O4/NPs) was used for modification of carbon paste electrode in the presence of paraffin oil and 1,3-dipropylimidazolium bromide (1,3-DPIBr) as binders. The modified electrode showed highly catalytic activity for electro-oxidation of epirubicin in biological condition. CoFe2O4 nanoparticle were synthesized by co-precipitation method with diameter of ~17.0nm and characterized with XRD and TEM methods. The chronoamperometry method was used to evaluate diffusion coefficient (Dapp) of the epirubicin in phosphate buffer solution pH=7.0. A calibration curve with sensitivity (0.1426μA/μM) was obtained for epirubicin in the concentration range 0.04–450μM at a surface of proposed electrode. Finally, the amplified sensor showed good ability of analysis of epirubicin in injection and serum samples.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
