Abstract
L6 rat myoblasts differ from T984 mouse myoblasts in the expression of several myogenic functions. Simple hybrids between these myogenic lines contained mostly chromosomes and expressed the mouse phenotype. Hybrids containing an approximately balanced set of chromosomes from each parent were constructed by fusing tetraploid L6 cells to T984 myoblasts. These hybrids were allowed to differentiate and their expression of myogenic proteins was compared to the parental phenotypes. The synthesis of creatine phosphokinase isoenzymes is codominantly expressed in the hybrid cells. Myosin light chain synthesis and the levels of acetylcholine receptor are either regulated by the mouse genome or are codominantly expressed.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
