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Abstract
Acute Generalized Exanthematous Pustulosis is a rare drug-induced skin disorder that can present at any age. It is typically noted by swelling and erythema, with numerous facial and/or anogenital nonfollicular pustules that quickly disseminate. Staphylococcal scalded skin syndrome presents with erythema and swelling that similarly favor the head and intertriginous sites with subsequent bullae formation. We present a case of a four-year-old female who presented with SSSS complicated by the development of AGEP and discuss the course of her condition and treatment.
Highlights
Patients with Acute generalized exanthematous pustulosis (AGEP) develop an abrupt febrile eruption of pinhead-sized nonfollicular pustules on an erythematous base favoring the face or intertriginous areas
We present a case of a four-yearold female whose diagnosis was
A previously healthy four-year-old female presented to her pediatrician with a fever of 101°F/38°C, facial edema, and a shiny erythematous eruption of her face, neck, and shoulders that spread to the neck and axilla overnight
Summary
Complicated by overlapping features of both SSSS and AGEP. Acute generalized exanthematous pustulosis (AGEP) is a disease of acute onset, typically following drug intake. A previously healthy four-year-old female presented to her pediatrician with a fever of 101°F/38°C, facial edema, and a shiny erythematous eruption of her face, neck, and shoulders that spread to the neck and axilla overnight. She developed rhinorrhea and shallow perinasal erosions with yellow crusting, leading to a diagnosis of bullous impetigo. The erythema continued to spread across the chest, down the back, and across the face with areas of vesiculation that ruptured, leading to crusts and scaling She developed radial fissuring around the mouth and eyes, clinically consistent with staphylococcal scalded skin. Upon discharge two days later, the patient completed a short course of oral cephalexin and TID application of triamcinolone cream 0.1% with complete resolution of skin lesions
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