Abstract
Acute hypofibrinogenemia, associated first with bleeding and then with hypercoagulability, developed in a patient with metastatic prostatic carcinoma. The hypercoagulability strongly suggests that intravascular clotting, rather than fibrinolysis, caused his acute hypofibrinogenemia. This case is thought to link the rare syndrome of acute hypofibrinogenemia with the common observation of venous thrombosis in malignancy.
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