Coexistence of relapsing polychondritis and remitting seronegative symmetrical synovitis with pitting odema (RS3PE) syndrome

Abstract

Relapsing Polychondritis (RP) is an autoimmune disease characterized by recurrent and progressive inflammation and destruction of cartilaginous and other proteoglycan-rich tissue with multisystematic manifestations. Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS3PE), is a rare disorder characterized by pitting edema, onset of acute polyarthritis and negative rheumatoid factor. A 46-year-old female patient who developed RS3PE after RP symptoms developed. This case, being an RS3PE syndrome accompanying RP and being a rare association, is presented to contribute to the literature.