Coexistence of Lack of Clinical Manifestation of Oral Mycosis and Systemic Diseases in Edentulous Patients Using Removable Prosthetic Restorations.

Izabela Gacon,Aneta Wieczorek

doi:10.3390/ijerph17176348

Abstract

Objective: It is believed that oral infections can increase the risk of systematic diseases, such as atherosclerosis and coronary heart disease, stroke, chronic obstructive pulmonary disease, diabetes, cancer, rheumatoid arthritis, etc. It seems that oral invasive pathogens induce a systemic inflammatory response via mediators released by the cardiovascular system and liver, which increases the risk to the patient of these systematic infections, such as hypertension. On the basis of previous studies of the stomatognathic system, investigating the coexistence of systemic diseases and inflammation in the oral cavity, it can be expected that there is a connection between inflammation of the denture-bearing area in patients using acrylic removable dentures and the presence of systemic diseases, and that patients with inflammation in oral mucosa are more likely to have systemic diseases. Material and method: A retrospective study was carried out on a group of patients seeking prosthetic treatment at the Prosthetic Department of the University Dental Clinic (UKS) from March 2012 to February 2013. All data were collected using a UKS electronic database with KS-SOMED. The minimum period of use for removable prostheses was five years. Results: According to anamnesis, the most common systemic diseases in our study group were hypertension disease. In total, 58% of patients with hypertension disease had no inflammation in the oral cavity. Conclusions: The occurrence of systemic diseases in edentulous people using removable prosthetic restorations, and the subsequent use of medications for these diseases, may result in a lack of clinical symptoms of concomitant fungal infection of the oral mucosa.

Highlights

Life expectancy in developed countries has increased over the last few decades, a change associated with the significant advances in medicine that offer a wide range of effective therapies for extending human life
Periodontal disease is one of the two most important oral diseases contributing to the global burden of chronic diseases [1]
On the basis of previous studies of the stomatognathic system investigating the coexistence of systemic diseases and inflammation in the oral cavity, it can be expected that there is a connection between inflammation of the denture-bearing area in patients using acrylic removable dentures and the presence of systemic diseases, and that patients with inflammation are more likely to have systemic diseases [14,15]

Summary

Introduction

Life expectancy in developed countries has increased over the last few decades, a change associated with the significant advances in medicine that offer a wide range of effective therapies for extending human life. An increase in the length of life does not always involve an increase in its quality. According to the World Health Organization (WHO), tooth decay remains widespread, with an incidence approaching 100% in some countries. The incidence of edentulism depends on the region and the country, as well as the age of patients; it most often occurs in people over 65 years of age [2]. By 2025, there will be over one billion people older than 60; by 2050, this group is expected to reach two billion people.

Methods

Results

Conclusion