Abstract
BackgroundInteratrial block (IAB) is an electrical conduction delay between the right and left atrium and is associated with some cardiovascular disorders. Arterial stiffness is a useful prognostic marker for cardiovascular events. In the present study, we aimed to investigate the coexistence of increased arterial stiffness and IAB in overweight subjects.MethodsA total of 110 overweight people were enrolled (56 subjects with IAB, and 54 age‐ and gender‐matched subjects without IAB) into the study. Surface 12‐lead standard ECGs were recorded. I.E.M. Mobil‐O‐Graph ambulatory blood pressure monitor device was used to assess the arterial stiffness.ResultsThe mean age of the patients was 54.1 ± 11.5 years, and 53.6% were male. PWV and Aix were significantly higher in IAB (+) group than IAB (−) group (9.34 ± 1.5 vs. 7.86 ± 1.3, p < .001; 29.18 ± 11.2 vs. 22.75 ± 10.4, p < .001, respectively), and also, positive linear correlation was observed between arterial stiffness parameters and P‐wave duration (r = .758 for PWV; r = .682 for Aix, respectively).ConclusionThe present study is the first to focus on evaluating the relationship between the presence of IAB and arterial stiffness in overweight subjects. If there is a coexistence of increased arterial stiffness and IAB in overweight subjects, it should be considered as requiring clinically closer follow‐up.
Highlights
Interatrial block (IAB) is an electrical conduction delay or block be‐ tween the right and left atrium
Arterial stiffness is a useful prognostic marker for cardiovascular events. It is influenced by age, gender, hypertension (HT), diabetes mellitus (DM), and smoking (Boutouyrie et al, 2002; Mitchell et al, 2010; Willum‐Hansen et al, 2006)
We thought that it may be useful to examine the cardiovascular involvement in overweight individuals before the development of "obesity cardiomyopathy." In the present study, we aimed to in‐ vestigate the coexistence of increased arterial stiffness and IAB in overweight subjects
Summary
Interatrial block (IAB) is an electrical conduction delay or block be‐ tween the right and left atrium. Arterial stiffness is a useful prognostic marker for cardiovascular events. Obesity represents a global health problem and is associated with cardiovascular risk factors It is a major predictor of cardiovas‐ cular disease (CVD) and mortality (Kannel & Benjamin, 2008; Lavie, Milani, & Ventura, 2009). It is known that obese patients have an increased arterial stiffness and high risk for developing IAB (Lurbe et al, 2012; Zebekakis et al, 2005). With the effect of these factors, fibrosis increases in cardiac tissue and "obesity cardiomyopathy" develops. We thought that it may be useful to examine the cardiovascular involvement in overweight individuals before the development of "obesity cardiomyopathy." In the present study, we aimed to in‐ vestigate the coexistence of increased arterial stiffness and IAB in overweight subjects
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