Abstract
AbstractCocrystallization can change the physicochemical and pharmacokinetic properties of active pharmaceutical ingredients (API) and improve biological activities. This study focuses on the documented biological activities of APIs in cocrystal form, specifically those with anticancer properties. Additionally, the mechanisms by which these APIs exhibit modified anticancer effects are discussed. Generally, this technique can change anticancer activity through solubilization, enhancing dissolution rate, permeability improvement, stabilization, producing a slow‐release form, and retaining transient in solution and interaction with receptors.
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