Abstract

While coccidioidomycosis is an uncommon infection in children in most of the United States, it is widely endemic in the arid regions of southern California, central and southern Arizona and New Mexico, and northwestern Texas.1 In those areas the frequency of positive coccidioidin skin tests is higher among children living in rural areas than among those living in urban areas. Positive coccidioidin skin tests are more common among darker-skinned children (e.g., in one area, Indian 60%, Spanish-American 42%, black 32%, white children 30%).2 Positive coccidioidin reactions are especially prevalent among Indian children living on reservations in central and southern Arizona, where 70% to 80% of all such children have been reported to have positive coccidioidin skin tests by the age of 14 years.3,4

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