COCCIDIOIDES IMMITIS MENINGITIS IN A PATIENT WITH HYPERIMMUNOGLOBULIN E SYNDROME DUE TO A NOVEL MUTATION IN SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION

Abstract

Hyperimmunoglobulin E syndrome (HIES) is a rare primary immunodeficiency characterized by recurrent skin and lung infections. We report the first case of Coccidioides immitis meningitis in a patient with HIES. Coccidioides should be included in the differential diagnosis for central nervous system infections in HIES patients.