Coccidioidal Endophthalmitis in Immunocompetent Person, California, USA

Michael L Cheng,Edward Ha,Matthew Leibowitz

doi:10.3201/eid1806.111765

Abstract

Coccidioidal Endophthalmitis in Immunocompetent Person, California, USA

Highlights

In October 2010, a 55-year-old white man in Santa Clarita, California, had severe pneumonia, drenching sweats, and an associated 25-pound weight loss
Aqueous fluid obtained intraoperatively grew mold, and the patient was admitted to the hospital for systemic antifungal therapy
The patient’s history was unremarkable except for avid mountain biking in the Central Valley of California. His physical examination was notable for left visual acuity limited to hand motion only, limited extraocular movement, conjunctival injection, and hypopyon

Summary

Introduction

In October 2010, a 55-year-old white man in Santa Clarita, California, had severe pneumonia, drenching sweats, and an associated 25-pound weight loss. In February 2011, the patient was referred to our institution, where an ocular ultrasound showed vitreous opacities (Figure). He underwent vitrectomy with intravitreal injection of empiric antimicrobial drugs, including voriconazole. Aqueous fluid obtained intraoperatively grew mold, and the patient was admitted to the hospital for systemic antifungal therapy.

Results

Conclusion