Cobalt(II) complexes of the antibiotic sulfadiazine, the X-ray single crystal structure of [Co(C 10H 9N 4O 2S) 2(CH 3OH) 2

Abstract

Cobalt(II) complexes of sulfadiazine formulated as [Co(C 10H 9N 4O 2S) 2(CH 3OH) 2] and [Co(C 10H 9N 4S) 2(H 2O) 2] have been synthesized and characterized by elemental analysis, infrared and UV–Vis spectroscopy and magnetic susceptibility measurements. The crystal structures of the complex [Co(C 10H 9N 4O 2S) 2(CH 3OH) 2] and of free sulfadiazine are also reported. The cobalt complex and the sulfadiazine ligand both crystallize in the monoclinic space group, P21/ c, with sulfadiazine acting as a bidentate ligand. Cobalt is coordinated to two-sulfonamide nitrogen and the pyrimidine nitrogen of the sulfadiazine. Two molecules of methanol complete the octahedral geometry around the cobalt, with interligand hydrogen bonding between methanol and sulfadiazine. Infrared spectroscopy confirmed the presence of water molecule in the coordination sphere of [Co(C 10H 9N 4S) 2(H 2O) 2]. The electronic spectra and magnetic moments of both complexes were similar, indicating that both complexes have similar structure.