Abstract
AbstractAn efficient C(sp2) – N cross coupling of cyclic and acyclic amides with styrenyl/aryl/heteroaryl halides catalyzed by cobalt acetylacetonate in combination with copper(I) iodide, has been achieved. A library of diversely substituted cyclic and acyclic enamides have been obtained in high yields by this procedure. The reaction is stereoselective producing (E)–enamides from trans‐styrenyl halides and (Z)‐ products from cis‐halides. This procedure has been successfully employed for the coupling of other N‐heterocycles such as pyrazole, imidazole and triazole with aryl/styrenyl/heteroaryl halides to produce the corresponding N‐coupled products. A probable mechanism has been suggested.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
