Abstract
Cobalt(II) salt as a non-noble metal catalyst has been widely used in direct C-H bond functionalization in recent years. In this work, we developed a cobalt-catalyzed C-H cleavage and alkoxylation of indoles with alcohols for the rapid construction of 2-alkoxylindole scaffolds. In the presence of Co(acac)2 as the catalyst, the reaction proceeds well to give a variety of 2-alkoxylindole derivatives in moderate to high yields. Control experiments suggest that a radical process might be involved in the reaction and the Co(III) species is the active catalyst.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
