Coats disease associated with vasoproliferative tumor treated with cryotherapy and intravitreal injections of triamcinolone

Leandro Cabral Zacharias,Taurino Dos Santos Rodrigues Neto,Epitácio Dias Da Silva Neto,Fernando Henrique Cardoso Antunes

doi:10.5935/0034-7280.20180061

Leandro Cabral Zacharias, Taurino Dos Santos Rodrigues Neto + Show 2 more

Open Access

https://doi.org/10.5935/0034-7280.20180061

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Abstract

Abstract Report of a case of Coats disease associated with retinal vasoproliferative tumor in a young female patient with two peripheral vascularized tumors and lipid exudation involving the macula and peripapillary region with serous retinal detachment areas and pre-papillary fibrous proliferation. The proposed and performed treatment was the intravitreal injection of triamcinolone acetonide to decrease the tumor exudation, followed by photocoagulation of the peripheral areas of telangiectasia without subretinal fluid and cryotherapy of the tumors. Despite that this is a rare and difficult to treat combination, in this case report, success was obtained in receding the tumor masses and reapplying the retina, leading to anatomic and visual stabilization.

Highlights

Coats disease is an idiopathic condition characterized by telangiectasia and aneurysms in retinal vessels, leading to subretinal and intra-retinal fluid
(1) Despite the presence of areas of capillary non-perfusion detected during fluorescein angiography, posterior segment neovascularization is unusual in these cases. [2]
The presence of exudation extending to the posterior pole, in addition to the diffuse leakage noted in fluorescein angiography examination confirmed the diagnosis of retinal vasoproliferative tumors secondary to Coats disease

Summary

Introduction

Coats disease is an idiopathic condition characterized by telangiectasia and aneurysms in retinal vessels, leading to subretinal and intra-retinal fluid. [1] Despite the presence of areas of capillary non-perfusion detected during fluorescein angiography, posterior segment neovascularization is unusual in these cases. [2]The disease affects men three times more than women and there are no reports of racial or ethnic predilection. Coats disease is an idiopathic condition characterized by telangiectasia and aneurysms in retinal vessels, leading to subretinal and intra-retinal fluid. The presence of exudation extending to the posterior pole, in addition to the diffuse leakage noted in fluorescein angiography examination confirmed the diagnosis of retinal vasoproliferative tumors secondary to Coats disease.

Results

Conclusion