Abstract
The present study compares the retention of four species that are often isolated in association with biomedical device-related infections – Staphylococcus aureus, Streptococcus mutans, Pseudomonas aeruginosa, and Candida albicans – to three different surfaces. All four bacterial species were found to bind significantly less well to MPC-coated surfaces than to non-coated surfaces. We attribute this effect to the “superhydrophilicity” of MPC-coated surfaces, whereas hydrophobic surfaces are well known to reduce bacterial retention and thus to inhibit a crucial step in the formation of bacterial biofilms that lead to biomedical device-related infections and complications.
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