Abstract
We present the case of a 24-year-old man, who was a keen runner, developing chronic bilateral lower leg compartment syndrome following co-administration of Risperidone and Sodium Valproate. Having had failed medical and physical therapies, he underwent surgical decompression of his more problematic left lower leg compartments. In the interval between sequential fasciotomies, control of his psychiatric symptoms allowed the dose of his Risperidone to be reduced, resulting in a greater exercise tolerance. Ultimately he no longer required the contra-lateral lower leg compartments to be decompressed surgically. He had returned to his original level of activity with no further psychotic episodes.
Highlights
All drugs exhibit side effects and when these are associated with acute surgical emergencies, doctors and nurses in specialties other than surgery and orthopaedics need to maintain an awareness of these
We attempt to highlight this with our case report on chronic exertional compartment syndrome with the co-ad
It seems clear that with initiation of Risperidone, this patient developed chronic bilateral lower leg exertional compartment syndrome, which abated on reduction in the dose of Risperidone
Summary
All drugs exhibit side effects and when these are associated with acute surgical emergencies, doctors and nurses in specialties other than surgery and orthopaedics need to maintain an awareness of these. Primary care physicians can be alert to chronic conditions but emergency doctors and nurses should realize that through knowledge and experience of the medical fraternity, conditions like compartment syndrome are less likely to be neglected. We attempt to highlight this with our case report on chronic exertional compartment syndrome with the co-ad-. How to cite this paper: Ray, R.K., Bashir, M.A. and Rao, S. (2014) Co-Administration of Risperidone and Sodium Valproate Causing Bilateral Chronic Exertional Lower Leg Compartment Syndrome.
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