Abstract

Ulcerative colitis (UC) is an autoimmune chronic inflammatory bowel disease. Tumor necrosis factor-α-antagonist monoclonal antibodies are first-line biologicals used in adult patients with moderate-to-severe UC. However, infliximab is the only approved biological therapy for children with UC. With this understanding, golimumab might be another option for pediatric moderate-to-severe UC. This study aims to evaluate the efficacy and safety of golimumab in pediatric UC patients.

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