Abstract

Sacubitril/valsartan (SAC/VAL) and angiotensin receptor blockers (ARB) are recommended therapy for heart failure with preserved ejection fraction (HFpEF), but little is known about their real-world comparative effectiveness and costs. We aimed to assess comparative effectiveness of SAC/VAL vs. ARB for preventing HF-related and all-cause hospitalizations in patients with HFpEF and their related medical costs.

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