Abstract
Pulmonary hypertension (PH) is a complex dise- ase with multifactorial etiology. Currently, a new definition and PH recognition is discussed if mean pulmonary artery pressure during right heart catheterisation is above 20 mm Hg (previo- usly > 25 mm Hg).In recent years, the use of so-called targeted therapy — focused on pathomechanisms of pulmonary arterial hypertension (PAH) contributed to improved survival in this group of patients. Further progress was made due to the development of new combined therapy strategies and escalation of treatment — in order to obtain patients’ low risk profile. Contemporary proceedings in PAH, in addition to the prompt diagnosis of the disease and the implementation of specialized treatment, include regular controls with a comprehensive assessment of exercise tole-rance, right ventricular function and the clinical status of patients.
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