Co(iii)-Catalyzed stereospecific synthesis of (E)-homoallylic alcohols with 4-vinyl-1,3-dioxan-2-ones: late-stage C–H homoallylation of indole derivatives

Abstract

An Co(iii)-catalyzed stereoselective C–H homoallylation reaction to access (E)-homoallylic alcohols was developed. This protocol provides a powerful approach for the late-stage C–H homoallylation of indole-based molecules.