CNS Complications of Varicella-Zoster Virus in the Postvaccine Era

Abstract

Encephalitis is the most common central nervous system (CNS) complication of infection with varicella-zoster virus (VZV), but stroke can also occur. Less common complications include Guillain-Barre syndrome and Ramsay-Hunt syndrome. Although VZV vaccination has reduced the incidence of primary varicella disease and associated complications (NEJM JW Pediatr Adolesc Med Jul 16 2014), risk remains in unvaccinated children. …