Abstract
The absence of lymph node involvement (N0) in gastric cancer is associated with a better survival. However some N0 gastric tumors still have a bad prognosis.To study demographic and morphological variables associated with prognosis in N0 gastric carcinoma.Review of pathological records of a regional general hospital, identifying patients with a N0 gastric cancer surgically excised between 1986 and 2003.In the study period, 459 gastrectomies were performed for gastric cancer and in 32%, the tumor was devoid of lymph node involvement. These later patients were followed for a median of 64 months with a 71% five years actuarial survival. Bivariate analysis identified age, tumor size, gastric wall infiltration, pathological type according to Lauren and Ming, lymphovascular involvement, number of lymph nodes excised and TNM stage as prognostic values Multivariate analysis disclosed the level of gastric wall infiltration, the presence of a poorly differentiated tumor, lymphatic vascular involvement, number of excise lymph nodes and tumor size as independent prognostic factors.N0 gastric tumors are found in 32% of gastrectomies for gastric cancer and have a 71% five years actuarial survival. Gastric wall infiltration, pathological degree of differentiation tumor size and lymphovascular involvement are independent prognostic factors.
Highlights
The absence of lymph node involvement (N0) in gastric cancer is associated with a better survival
Aim: To study demographic and morphological variables associated with prognosis in N0 gastric carcinoma
In the study period, 459 gastrectomies were performed for gastric cancer and in 32%, the tumor was devoid of lymph node involvement
Summary
The absence of lymph node involvement (N0) in gastric cancer is associated with a better survival. Results: In the study period, 459 gastrectomies were performed for gastric cancer and in 32%, the tumor was devoid of lymph node involvement. These later patients were followed for a median of 64 months with a 71% five years actuarial survival. Tumor size, gastric wall infiltration, pathological type according to Lauren and Ming, lymphovascular involvement, number of lymph nodes excised and TNM stage as prognostic values. Con la finalidad de explicar este errático comportamiento de algunos carcinomas gástricos pN0, autores han realizado estudios enfocados a la identificación de variables clínicas y morfológicas asociadas al pronóstico de pacientes resecados por CG pN0 con intención curativa (R0), demostrando ellos entre los principales factores relacionados al pronóstico el tamaño tumoral, nivel de infiltra-. El objetivo de este estudio fue comparar las características clínico-patológicas de pacientes con CG pN0 y N+ junto con determinar la existencia de asociación de estas variables con la SV de pacientes resecados por CG pN0
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