Abstract
Sarcoidosis is a multisystemic disorder of unknown aetiology characterised by the formation of noncaseating epithelioid cell granuloma involving various organ systems. Cardiac involvement has an important prognostic factor as it can present with life-threatening arrythmias and sudden death. Here, we present a case of cardiac sarcoidosis in a 46-year-old gentleman who presented with nonspecific signs and symptoms. We also discuss diagnostic difficulties especially when cardiac involvement is the only clinical sign. In this case, cardiac magnetic resonance (CMR) played an important role in the diagnosis and followup of our patient.
Highlights
Cardiac sarcoidosis is an important cause of death in patients with systemic sarcoidosis
Cardiac sarcoidosis is an important cause of death in patients with systemic sarcoidosis and should be considered in those who demonstrate cardiac symptoms and/or signs
Clinical manifestations of cardiac sarcoidosis depend on the location and extent of granulomatous infiltration and include conduction abnormalities, ventricular and supraventricular arrythmias, heart failure, valvular dysfunction, simulated infarction, and cor pulmonale
Summary
Cardiac sarcoidosis is an important cause of death in patients with systemic sarcoidosis. 20–30% of patients with systemic sarcoidosis have evidence of granulomatous infiltration of the myocardium at autopsy [1]. The presence of scar tissue in the myocardium increases the risk of malignant arrhythmias, and up to 60% of fatalities from cardiac sarcoidosis present as sudden cardiac death [2]
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