Abstract
Background Transcatheter Aortic Valve Implantation (TAVI) is the treatment of choice for patients with severe symptomatic aortic stenosis (AS) who are at high surgical risk. AS results in changes in myocardial strain and twist. Myocardial strain, strain rate and twist can be measured with myocardial tagging CMR. It is not known how TAVI affects LV diastolic and systolic function as measured by CMR tagging.
Highlights
Transcatheter Aortic Valve Implantation (TAVI) is the treatment of choice for patients with severe symptomatic aortic stenosis (AS) who are at high surgical risk
Following TAVI, peak Lagrangian circumferential strain increased in the mid-LV (-0.19 ± 0.06 vs. -0.22 ± 0.07, P = 0.03)
There was no significant change in apical (-0.20 ± 0.06 vs. -0.20 ± 0.07, P = 0.81) or basal (-0.19 ± 0.06 vs. -0.20 ± 0.06, P = 0.24) circumferential strain
Summary
Transcatheter Aortic Valve Implantation (TAVI) is the treatment of choice for patients with severe symptomatic aortic stenosis (AS) who are at high surgical risk. AS results in changes in myocardial strain and twist. Myocardial strain, strain rate and twist can be measured with myocardial tagging CMR. It is not known how TAVI affects LV diastolic and systolic function as measured by CMR tagging. Academic Unit of Cardiovascular Medicine, Multidisciplinary Cardiovascular Research Centre (MCRC) & The Division of Cardiovascular and Diabetes Research, Leeds Institute of Genetics, Health and Therapeutics, Leeds, UK
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