Cluster structure inference for microarray data based on an information theoretic criterion

Abstract

This paper presents a new method for estimating the number of clusters and cluster structure in microarray data sets, based on minimum description length (MDL) principle and normalized maximum likelihood (NML) model for linear regression. The cluster-structure models for microarray data are compared based on the MDL principle. The performance of the new method is studied using simulated and real microarray data sets.