Abstract
Recently, 14 persons in southeastern Florida were identified with Neisseria meningitidis serogroup W135 invasive infections. All isolates tested had matching or near-matching pulsed-field gel electrophoresis patterns and belonged to the multilocus sequence type 11 clonal complex. The epidemiologic investigation suggested recent endemic transmission of this clonal complex in southeastern Florida.
Highlights
14 persons in southeastern Florida were identified with Neisseria meningitidis serogroup W135 invasive infections
Isolates from outbreaks or clusters are further characterized by pulsed-field gel electrophoresis (PFGE) by using NheI and SpeI restriction enzymes and methods consistent with standard protocols [2]
From December 2008 through April 2009, we observed an increase of invasive meningococcal disease caused by serogroup W135 in southeastern Florida totaling 13 patients, of whom 9 had indistinguishable PFGE pat
Summary
14 persons in southeastern Florida were identified with Neisseria meningitidis serogroup W135 invasive infections. From December 2008 through April 2009, we observed an increase of invasive meningococcal disease caused by serogroup W135 in southeastern Florida totaling 13 patients, of whom 9 had indistinguishable PFGE pat- Isolates from the 4 other case-patients had PFGE patterns differing by 1 (pattern II), 2 (pattern III), and 5 bands (pattern IV), making them >94% related to the dominant pattern.
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