Clues Emerge on How HIV Increases Lymphoma Risk

Abstract

Two recent studies provide new clues to why people infected with human immunodeficiency virus (HIV) are at high risk — sometimes very high risk--for lymphoma. One of the studies adds new data linking macrophages in HIV patients with the development of AIDS-related lymphoma (ARL). The other suggests that AIDS patients who develop lymphoma have higher levels of certain cytokines as early as 2 years before their diagnosis. The fi ndings could lead to new prevention and treatment strategies not only for ARL but also for other types of lymphoma, according to the researchers, who presented their fi ndings in April at the annual meeting of the American