Closure of idiopathic full-thickness macular hole after intravitreal C3F8 injection without vitreomacular traction release: A case report and review of literature.

Abstract

To describe a successful closure of macular hole without release of vitreomacular traction (VMT) after intravitreal perfluoropropane (C3F8) gas injection. A 54-year-old woman was referred to our clinic with the history of declined vision after a period of distorted vision in her right eye. After dilated fundus examination and performing optical coherence tomography (OCT), a V-shaped VMT complicated by full-thickness macular hole was diagnosed and she underwent pneumatic vitreolysis using intravitreal C3F8 gas injection. After 12 weeks, her visual acuity was significantly improved and fundus examination and OCT revealed that the macular hole was completely resolved despite persisted VMT. Intravitreal gas injection would be a promising option to manage idiopathic macular holes not only by releasing the vitreous traction on the macula, but also through some not proven or even unknown mechanisms.