Abstract
Clostridium tertium bacteremia is a rare condition that predominantly occurs in neutropenic patients. Clostridium tertium bacteremia, although extremely rare in non-neutropenic patients, represents the second-most common cause of bacteremia among Clostridium species. Infection with this bacteria can present variably and is usually managed with broad-spectrum antibiotics.
Highlights
Clostridium tertium (C. tertium) is an unusual cause of bacteremia, but when found, it is ordinarily seen in neutropenic patients
We report a case of C. tertium bacteremia in a non-neutropenic patient with spontaneous bacterial peritonitis secondary to cirrhosis
Ascitic fluid analysis showed 492 neutrophils/μL, which pointed to spontaneous bacterial peritonitis (SBP); ascitic fluid cultures were negative
Summary
Clostridium tertium (C. tertium) is an unusual cause of bacteremia, but when found, it is ordinarily seen in neutropenic patients. C.tertium bacteremia in non-neutropenic patients is very rare. We report a case of C. tertium bacteremia in a non-neutropenic patient with spontaneous bacterial peritonitis secondary to cirrhosis. Blood cultures on admission grew gram-positive rods after Day 1. Repeat blood cultures on Days 2 and 3 grew gram-positive rods as well. By Day 5, four out of four blood cultures grew Clostridium tertium sensitive to penicillin, meropenem, and metronidazole (Figure 1). How to cite this article Wazir M, Jain A G, Nadeem M, et al (April 11, 2019) Clostridium tertium Bacteremia in a Non-neutropenic Patient with Liver Cirrhosis. Despite supportive care in the intensive care unit, he had recurrent seizures, shock, and respiratory failure, necessitating vasopressor and ventilatory support
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