Abstract
BackgroundClostridium perfringens is an uncommon pathogen in endophthalmitis, causing rapid destruction of ocular tissues. Clostridium perfringens infection typically occurs after penetrating injury with soil-contaminated foreign bodies.Case reportHere, we describe the case of a 17-year-old male who sustained a penetrating injury with a metallic intraocular foreign body and who rapidly developed severe C. perfringens panophthalmitis with orbital cellulitis. He was managed by systemic and intravitreal antibiotics, resulting in preservation of the globe, but a poor visual outcome.ConclusionClostridial endophthalmitis secondary to penetrating injuries is a fulminant infection, almost always resulting in loss of the globe in the case of advanced infection. When feasible, early vitrectomy and intravitreal antibiotics should be considered in patients with penetrating eye injuries with contaminated foreign bodies.
Highlights
Clostridium perfringens is an uncommon pathogen in endophthalmitis, causing rapid destruction of ocular tissues
Early vitrectomy and intravitreal antibiotics should be considered in patients with penetrating eye injuries with contaminated foreign bodies
The visual prognosis is determined by the anatomic site of the intraocular foreign body (IOFB), as the majority of IOFBs are located in the posterior segment of the eye, which is associated with a poorer visual prognosis than those located in the anterior segment [2,3,4]
Summary
This case report highlights the fact that, due to the rapidly devastating outcome, penetrating eye injuries with soil-contaminated foreign bodies must be considered to be at high risk for clostridial infection and a b. Vitrectomy and early removal of foreign material from the eye is important because this removes the growth media and potential source of infection. Vitrectomy reduces the inoculum of harmful pathogens. 7. Hsu HY, Lee SF, Hartstein ME, Harocopos GJ. Clostridium perfringens keratitis leading to blinding panophthalmitis. Macular infarction after endophthalmitis treated with vitrectomy and intravitreal gentamicin. The role and timing of pars plana vitrectomy in penetrating ocular trauma. Controversies in the management of open-globe injuries involving the posterior segment.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
