Abstract
IntroductionHuman teeth are composed mainly of dentin, formed by the odontoblasts. Dentin matrix protein 1 (DMP1) is one of odontoblast differentiation's most important growth factors. Human DMP1 has yet to be completely identified or studied. This study aimed to clone and characterize human DMP1. Materials and methodsThe DMP1 gene sequence was prepared and cloned by transfection of human 293 cells. ResultsThe recombinant DMP1 was purified and characterized. ConclusionThe results suggested its future use in dental tissue regeneration and tissue engineering.
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