Abstract
A Xenopus laevis gene was cloned on the basis of cross-homology to a region conserved between several Drosophila homeotic genes. It was shown to be expressed during early development, starting at late gastrulation and producing three transcripts under specific temporal control. The frog gene contains a region coding for 60 amino acids, which is extremely conserved when compared to Drosophila homeotic genes in the region of the homeo domain. Southern blot analysis indicates that there are at least five such sequences in the Xenopus genome. The conserved region is very rich in arginine. This gene could perhaps represent the first development-controlling gene identified in vertebrates.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
