Abstract
The secreted aspartyl proteinase 4 (SAP4) of Candida albicans contribute to Candida albicans colonization and immunopathogenesis, therefore, become a target for Candida albicans therapy and vaccine development. However, data of the Candida albicans SAP4 from Indonesian isolate is limited. To study the Candida albicans SAP4, a complete coding sequence of Candida albicans SAP4 gene was cloned from Candida albicans genomic DNA isolated from a Javanese HIV/AIDS patient. The clone was sequenced and subjected to bioinformatics analysis. Physicochemical analysis revealed the molecular weight (Mw), estimated half-life, instability index, isoelectric point, aliphatic index, and hydrophilicity of the SAP4 protein. The antigenicity and epitope prediction also had been discussed. The results of this study would contribute information about Candida albicans SAP4 from Indonesian isolate.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
