Abstract

Also called persistent cloaca..The dilated sac like structure in the center of the abdomen. There has been failure in early fetal life of the urorectal septum to divide the rectum from the urogenital inus. Entering the cloaca are the colon, the right ureter and the left ureter (there was left renal agenesis), 2300 m.l fluid was collected from cloaca. The cloaca served as rectum and bladder. The infant had no anus. The only outlet was a thin narrow urethra. PERSISTENT CLOACA. Etiology- Unknown. Pathogenesis- The abnormality results from failure of the urorectal septum to separate the primitive urogenital sinus from the hindgut. General Gross Description - The diagnosis rests on the gross demonstration of a common structure serving as bladder and rectum. General microscopic Description- not applicable. Clinical correlation - Associate anomalies may include imperforate anus, abscence of genital and urinary orifices,renal agenesis. derivatives of forgut, midgut is not well develop, absence of the prostate and seminal vesicles. Epitilial lined muscular viscus that can distended and hold up to 2300 ml of urine without a change in intra luminal pressure. Trigone, genital and urinary orifices are absent. Rt kidney is normal,left kidney is hypoplastic. Entering the cloaca are the colon,the right and left ureter. References Text book of fetal and perinatal pathology, Lengman’s medical Embryology 6th edit.

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