Abstract

Introduction: Recently NOTES procedures have enjoyed much popularity. An important issue to be solved is the most reliable method of closing the full thickness gastrointestinal wall incision (FTGI). Clip closure (CC) is sometimes successful in patients but surgical repair remains the gold standard. New prototype endoscopic suturing (EC) has recently produced interesting results in animal models. Aim: to compare the performance of CC and histology of the esophageal defect repair with newly developed EC using anchor/locks and surgical thoracoscopic repair (TC) of a standardized 2-2.5 cm esophageal FTGI.

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