Abstract
In the past half-century, considerable attention has been paid to oral and maxillofacial skeletal cyst, however, aneurysmal bone cyst (ABC), unlike other common bone diseases, still contours numerous unanswered questions in terms of classification, etiology and pathological mechanism. The purpose of this article was to evaluate the proportion of primary ABC and secondary ABC, and to assess the recurrence of ABC and related factors. A methodical search of Embase, MEDLINE, Cochrane Library, Web of Science was conducted for well-documented jaw aneurysmal bone cyst (JABC) cases. One hundred thirty-one articles were identified after database searching and 31 of them were included in our study for further research with 44 JABC cases. All the articles were analyzed by two separate authors. About 25% of the reported jaw aneurysmal bone cyst was secondary. Both the pathological classification and surgical treatment had a significant influence on recurrence rate (P = 0.0082, P = 0.0022), while patients' age or radiographic features rarely affected prognosis. Jaw aneurysmal bone cysts can present variable clinical and histological presentations. Recurrence may be attributed to omittance of underlying potential blood supply or conservative surgical protocol.
Highlights
Aneurysmal bone cyst (ABC) is a common skeletal bone lesion that usually observed in long bones and vertebra
This review aims to evaluate the proportion of primary ABC and secondary ABC, and to assess the recurrence of ABC and related factors, which has certain clinical significance for the diagnosis of oral and maxillofacial skeletal cyst
After excluding articles as per criteria, 31 articles with 44 jaw aneurysmal bone cyst (JABC) cases were included in the present review, with 22 (50%) males and 22 (50%) females ranging in age from 3 to 48 years
Summary
Aneurysmal bone cyst (ABC) is a common skeletal bone lesion that usually observed in long bones and vertebra. JABC presents itself as a rapid-growing, painful or painless, swelling defect with or without bony expansion [1]. In some cases, it may be misdiagnosed as a malignant disease. A review has updated the recurrence rate of head and neck ABCs with 94.4% patients free of disease in the average follow-up period of 3.59 years [2]. This result was widely different from the old ones, which ranged from 21 to 50%. The risking factors of ABC recurrence remains an ongoing challenge due to the diverse clinical features and pathogeny
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