Clinicopathological study of gastrointestinal Lymphomas and their survival in the patients referred to Yazd hospitals during 2011 to 2016

Abstract

Introdution: Malignant lymphoma is divided into two subgroups of Hodgkin's and non-Hodgkin's, and 40% of them occur in areas other than the lymph node, the most common being the digestive tract. According to studies, in recent years the prevalence of non-Hodgkin's lymphomas has increased over the past. Therefore, in this study, we investigated the gastrointestinal lymphoma and the survival rate of the patients with this disease based on clinicopathologic characteristics.
 Methods: This study was an analytic-cross sectional study. The study population included 97 patients with various types of gastrointestinal lymphoma referring to 3 hospitals in Yazd during 2011-2011. Sampling was done by census. Referring to pathology department of hospitals, all cases related to gastrointestinal tract lymphoma extracted and the information (age, sex, year of diagnosis, type of lymphoma, location of lymphoma, treatment method and survival rate) using the checklist was recorded. The data were analyzed by SPSS18 software and patients' survival was assessed using Kaplan-Meier curves and Log-Rank test.
 Results: The results of the study showed that out of 97 patients, 69 patients (71.1%) were male and 28 (28.9%) were female. The mean age of the patients was 49.28±21.5. The most common site of lymphoma was stomach (45.4%), the most common type of treatment, surgical+ chemotherapy (53.6%), and the most common type of lymphoma, B cell lymphoma (50%). The mean survival time was 48 months and there was a significant relationship between mean survival time according to type of treatment.
 Conclusion: According to the results, it can be concluded that the appropriate treatment for patients with gastrointestinal lymphomas is surgical+chemotherapy combination therapy.