Clinicopathological study of 400 endometrial curettage samples at rural tertiary care centre

Abstract

Introduction: An endometrial sampling procedure is a gold standard for the diagnostic evaluation of women with abnormal uterine bleeding (AUB) with primary aim to identify the cause, especially to determine whether carcinoma or premalignant lesions are present. Abnormal uterine bleeding (AUB) is the commonest presenting symptom in gynaecology outpatient department. Here we are presenting a study of 400 endometrial curettage samples with regard to the clinic-pathological findings. Objectives: This study was done to evaluate 400 endometrial curettage samples clinicopathologically at a rural tertiary care centre. Material and Methods: A total of 400 endometrial curettage samples were processed and H & E staining was done. Special staining and IHC was done wherever required. Clinicopathological correlation was done in all the cases and the results are compared to other studies. Results: In our study of 400 endometrial curettage samples, the minimum age observed was 18 years and maximum age of 70 years with most common age group was between 31-40 years. The commonest findings were of cyclical changes in the endometrium followed by abnormal endometrial pathology and trophoblastic diseases. Conclusion: Endometrial biopsy is an important tool to diagnose gynaecological conditions in patients. It is important to know the histological pattern of the endometrium in abnormal uterine bleeding in different age groups since it will help in the management of the cases. Postmenopausal bleeding should be considered as an indication of malignancy until proved otherwise.