Clinicopathological Profile Of Her2 Positive (Non-Luminal) Breast Cancer Subtype At Haji Adam Malik General Hospital From 2020-2021

Abstract

Background: Breast cancer is one of the cancers with the highest prevalence in Indonesia. According to GLOBOCAN data for 2020, the number of breast cancer cases reached 68,858 (16.6%) cases out of a total of 396,914 new cancer cases in Indonesia. There are many factors that can trigger cancer with different clinical manifestations and subtypes from one event to another, so researchers are interested in researching the profile of breast cancer patients with the HER2 subtype at H. Adam Malik General Hospital in 2020-2021.Objective: In the present study, we aim to determine the clinicopathological profile of Her2 positive (non-luminal) breast cancer subtype patients at Haji Adam Malik General Hospital from 2020-2021.Methods: The method used in this study is descriptive quantitative with total sampling technique. The data samples was obtained from medical records of breast cancer patient with her2 positive (non-luminal) subtype which was then sorted according to the availability of characteristic needed for this study. Results: majority of breast cancer patients with her2 positive (non-luminal) subtype at H Adam Malik General Hospital in 2020-2021 was within the age group of > 50 years, with all married status. the BMI of the majority of patients (68.6%) was normal weight, all respondent admit there was no family history diagnosed with cancer (100%), majority tumor size (52,9%) is >5 cm, with most patients having cancer metastasized to 1-3 lymph nodes (54,9%), distant metastases only in 39,2% of the total sample observed, majority (35,3%) histopathological degree is in grade 1 and grade 3 , the histopathological classification of the majority (86,3%) was IDC type. Conclusion: Overall there is diversity of frequencies within the observed clinicopathological characteristics.