Abstract
Background:Anorectal melanoma (AM) is a rare subtype of melanoma.Aim:To study the clinic–pathologic features and outcomes in patients with AM.Materials & methods:Clinical, pathologic findings and outcomes of patients with AM were recorded.Results:Twenty-seven patients with AM were identified with median age of 57 years. Most patients presented in stage III (44.4%). Lymph node involvement was seen in 70.4%. The response to chemotherapy and immunotherapy was 16.6 and 25.0%, respectively. At a median follow up of 11 months, median overall survival was 30 months. Ballantine stage 3 and weight loss at presentation were predictors of poor survival.Conclusion:AM presents at an advanced stage with lymph node and distant metastasis.
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