Clinicopathological characteristics and prognosis of remnant gastric cancer

Abstract

Objective To investigate the clinicopathological characteristics and prognostic factors of remnant gastric cancer. Method Took a retrospective analysis on the clinical data of 48 patients with remnant gastric cancer from March 1992 to September 2009. Results Of these 48 cases,32 had lesion at anastomotic site and the remaining 16 located in non-anastomotic site. The histological type included 2undifferentiated adenocarcinoma,32 poorly differentiated adenocarcinoma, 12 moderately differentiated adenocarcinoma and 2 well differentiated adenocarcinoma. The pathological stages included stage Ⅰ 5 cases,stage Ⅱ 6 cases,stage Ⅲ 28 cases and stage Ⅳ 9 cases. The 1-year,3-year and 5-year survival rates in patients with the radical treatment were 100.0% ,65.4% and 32.5% respectively, and which were significantly higher than those in patients without radical treatment (28.5% ,12.2% ,0),the difference was statistically significant (P＜0.05). The 5-year survival rates of pathological stage Ⅰ , Ⅱ , Ⅲ and Ⅳ were 100.0%,66.7% ,21.4% and 0 respectively, the differences between the various stages were statistically significant (P＜ 0.05). Conclusion The remnant gastric lesions are mainly located near the anastomosis, the prognosis of remnant gastric cancer is closely related to whether taken radical surgery and the tumor's pathological stage. Key words: Neoplasm,residual; Pathology,clinical; Prognosis